Alcohol is one of the most commonly consumed substances in the world, exhibiting complex relationships with multiple aspects ...

BACKGROUND: Previous research suggests that exposures to air pollution and nonoptimal temperatures are associated with a ...

BACKGROUND: Recent studies have highlighted the deleterious role of high phosphate intake in hypertension by means of ...

BACKGROUND: Despite the significant global impact of the COVID-19 pandemic, limited studies have investigated the long-term ...

The win ratio is a method for analyzing a hierarchical composite outcome. It has been most widely used in randomized clinical trials (RCTs) in cardiovascular disease. We performed a review of ...

Department of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China (C.X., C.W., J.W., X.W., C.K., J.N., H.D., Y.X., Y ...

Cardiac metabolic dysfunction is a hallmark of heart failure (HF). Estrogen-related receptors ERRα and ERRγ are essential regulators of cardiac metabolism. Therefore, activation of ERR could be a ...

Myocardial ischemia/reperfusion (I/R) injury is a substantial challenge to the management of ischemic heart disease, the leading cause of mortality worldwide. Arachidonic acid (AA) is a prominent ...

The “open vein hypothesis” postulates that early thrombus clearance and restoration of venous blood flow may prevent postthrombotic syndrome after proximal deep vein thrombosis. Since its proposal ...

Dilated cardiomyopathy (DCM) is substantially influenced by genetic factors. Sarcomere function is intricately associated with other organelles, particularly the reciprocal regulation between ...

Several widely recognized AF risk factors, listed by the National Heart, Lung, and Blood Institute, are related to pulmonary issues, including obstructive sleep apnea (OSA), chronic obstructive ...

Heart failure with preserved ejection fraction (HFpEF) is one of the most common forms of heart failure; its prevalence is increasing, and outcomes are worsening. Affected patients often experience ...