Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...

Now the researchers have come closer to understanding how the ribosome works. "It is amazing that we can visualize the atomic details of the ribosome. Because they are tiny—around 20–30 ...

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor ...

A central tenet of biology has long held that each amino acid added to a peptide chain is specified by an RNA message as it threads its way through the ribosome. But Howard Hughes Medical Institute ...

Ribosomal translation is the process by which cells synthesize proteins based on the genetic instructions encoded in messenger RNA. It is essential for life, yet it is an incredibly complex process ...

Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

Transmission electron micrograph of negatively stained FloV-SA2 virus particles (top left). Scale bar: 100 nm; A ribosome ...

Researchers at the University of Hawaiʻi at Mānoa have made an exciting discovery : a virus found in the ocean called FloV-SA2 carries the genetic ...

Although only a few rRNA molecules are present in each ribosome, these molecules make up about half of the ribosomal mass. The remaining mass consists of a number of proteins — nearly 60 in ...

Within the ribosome, the mRNA and aminoacyl-tRNA complexes are held together closely, which facilitates base-pairing. The rRNA catalyzes the attachment of each new amino acid to the growing chain.

The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...