Using genetically defined zebrafish models, the authors can inducibly express ... Cre-activated (CreER fusion that becomes active with light-induced uncaging of a tamoxifen-analogue in a targeted ...

This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...

Combined use of fast track PDX models (chicken chorioallantoic membrane and larval zebrafish) with conventional murine models enabled rapid response modeling while achieving tumor expansion for ...

Tamoxifen, which is prescribed for the treatment of breast cancer, can interact with some commonly used drugs and over-the-counter nutritional supplements. You may be taking tamoxifen for at least ...

Urology Research Laboratory, Department for BioMedical Research, University of Bern, Bern 3010, Switzerland Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern 3010, ...