eLife5d
Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
This manuscript demonstrates that Oct4 overexpression synergizes with Notch inhibition (Rbpj knockout) to promote the conversion of adult murine Müller glia (MG) into bipolar cells. These findings are ...
The EMBO Journal6d
Proteomics and personalized PDX models identify treatment for a progressive malignancy within an actionable timeframe
Combined use of fast track PDX models (chicken chorioallantoic membrane and larval zebrafish) with conventional murine models enabled rapid response modeling while achieving tumor expansion for ...
C&EN5d
Peptide-Modified Lipid Nanoparticles Boost the Antitumor Efficacy of RNA Therapeutics
Urology Research Laboratory, Department for BioMedical Research, University of Bern, Bern 3010, Switzerland Department of Urology, Inselspital, Bern University Hospital, University of Bern, Bern 3010, ...