However, most therapeutic agents, especially chemotherapy, have no intrinsic affinity for tumor vessels, which can cause severe drug resistance and systemic side effects. An increasing number of ...

Here we present a series of remarkable microscope views of various stages in cancer growth and angiogenesis, or growth of new blood vessels. Shot during experiments with laboratory chicken embryos ...

Among the CAMs, VCAM-1 is overexpressed in tumor vessels and is an attractive target for anticancer drug delivery. It is said to promote the binding between leukocytes and endothelial cells by ...

Innovative diagnostic approaches: Serum protein markers in renal cell carcinoma. Comprehensive proteomic profiling of plasma samples associated with response or resistance to immune checkpoint ...

the team employed multistep non-invasive intravital microscopy and revealed that the BM that surrounds the endothelial cells and mural cells of tumor vessels severely impede the extravasation of ...

Glioblastoma is a brain cancer with very poor survival outcomes ... Researchers are using 3D bioprinting to create artificial ...

(see p.1185) describe the generation of a modified TNF molecule bearing an N-terminal peptide that targets it to CD13, a cell surface molecule expressed on tumor vessels. The modified molecule ...

Deepening the betrayal, the body itself becomes complicit. Blood vessels grow toward the tumor, supplying oxygen and nutrients. Immune cells may forego an attack on the cancer and protect it instead.

In addition to a sonoporation-augmented delivery increase, multiple other cellular Modes of Action change the receive characteristics of cells, including one that enhances radiosensitization of tumors ...

Researchers have uncovered a surprising layer of complexity in aldosterone-producing adenomas -- adrenal gland tumors that drive high blood pressure. Using cutting-edge analysis techniques, they ...