Axonal injury, often termed diffuse axonal injury (DAI), is a common consequence of brain injury and is associated ... in individuals experiencing a traumatic event to mobilize the optimal ...

and traumatic brain injury (TBI) are associated with neuroinflammation, excitotoxicity and increased oxidative stress. Axonal dysfunction is a major obstacle to recovery in TBI and SCI.

says a preclinical rat study showed its peptide drug candidate ARG-007 offered “significant neuroprotection” against traumatic brain injury (TBI). The study assessed key markers of axonal ...

Traumatic brain injury (TBI) leads to increased rates of dementia, including Alzheimer’s disease. The mechanisms by which trauma can trigger neurodegeneration are increasingly understood. For example, ...

Cell replacement-based therapeutic approaches using exogenous Schwann cells could be curative, but not all Schwann cells have a “repair” phenotype, defined as the ability to promote axonal ... injury) ...

traumatic injury and disease as they relate to endothelial cells and the BBB here in order to highlight the importance and difficulty of disentangling these effects from the response to electrical ...

One in 60 people in the U.S. lives with a traumatic brain injury related disability. Here, we discuss the long-term effects ...

Addressing the harmful chemical processes that accompany blunt force trauma to the brain can reduce the risk of long-term ...

Traumatic brain injury is a leading cause of death and disability in the world. Blunt force trauma to the brain, often from a ...