Thus, targeting epigenetic factors that change the accessibility of the chromatin could help regulate stem cell lineage plasticity and restore proper stem cell function. We started off by studying the ...

Vanishing White Matter Disease (VWMD) affects brain function due to reduced eIF2B activity. New research uncovers how cells ...

A new study reveals that memory-related brain activity continues to shift even after learning, challenging traditional views ...

Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies ...

Questions regarding the plasticity in differentiation have led to a debate about the potential of cells to 'transdifferentiate' or to 'reprogramme' themselves. These issues can be addressed not ...

When these cells differentiate to make specialized cells and tissues, they gradually lose their plasticity, or ability to change into different kinds of cells. A one-week old embryo only contains ...

New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...

Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies ...

therapy resistance and lethality of metastatic cancer is driven by dynamic and tenacious metastasis stem cells (MetScs). The Ganesh lab focuses on understanding the molecular mechanisms that underlie ...

“The cells dedifferentiate back into a type of regenerative stem ... H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium. Nat Cell Biol. 2025;27(2):202-217. doi: ...