During a live event, Neal E. Ready, MD, and participants discussed what factors justify using PD-1 plus CTLA-4 inhibitor and ...

During endocrine therapy, rising CA15-3 levels suggested progression. FDG PET/CT confirmed progression with multiple hypermetabolic lesions, raising concern about the current ER status. FES PET/CT ...

Subchondral sclerosis is the hardening of the tip of a bone just below the cartilage. It shows up in the later stages of osteoarthritis. Learn about symptoms, diagnosis, and treatment.

Melorheostosis is a rare bone disease that presents as sclerotic lesions growing on existing bone surfaces. This disease is of unknown etiology and affects both genders equally. The disease is unique ...

Bone scan requested as part of routine examination for disease staging. The whole-body planar images showed focal increase radiotracer activity at the right side of the pelvis (Figure 3), which ...

We define 4 PCBM phenotypes: osteolytic, mixed lytic-sclerotic, and 2 subgroups of osteosclerotic lesions-those with residual trabeculae, and others without residual trabeculae. The osteosclerotic ...

Most people with MS facial twitching have a lesion in a certain part of the brainstem called the pons. Important nerves go in and out of the brainstem through a bony canal.

A 56-year-old female presented with popliteal venous thrombosis, splenomegaly, and sclerotic bone lesions. Bone marrow biopsy showed fibrosis, proliferation of abnormal blood vessels and lymphatics, ...

To further evaluate the prostatic lesion, a biopsy was performed revealing adenocarcinoma in both the left midgland (Gleason 6, grade I) and the left base (Gleason 7, grade II). 68 Ga-PSMA-11 PET/CT ...

A new case has been published of a novel cytogenetic abnormality in a patient with systemic mastocytosis (SM). The case, published in the British Journal of Haematology, involved a focal deletion of ...

This work presents a computer-aided detection (CAD) system to aid radiologists in finding sclerotic bone metastases in the spine on CT images. The spine is first segmented using thresholding, region ...

Radium-223 is a bone-seeking, alpha-emitting radionuclide used to treat men with bone metastases from castration resistant prostate cancer (mCRPC). Sclerotic bone lesions are non-evaluable by RECIST.