In all instances, the σ-hole was deeper and formed a stronger bond with the nucleophile NH 3. These findings advance our fundamental knowledge of non-covalent interactions based on σ- and π-holes and ...

Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...

Due to the non-symmetrical shape of the molecule (bent), the molecule itself is polar (it has a \(\delta-\) and \(\delta+\) side). Carbon tetrachloride has four polar covalent bonds. It is a ...

A covalent bond is a shared pair of electrons between two non-metal atoms, for example carbon dioxide. Figure caption, Two atoms sharing a pair of electrons. A covalent bond happens when the ...

with a large difference indicating a polar covalent bond (e.g., H-F bond) and a small difference indicating a non-polar covalent bond (e.g., C-C bond). Electronegativity is crucial for explaining ...