The monocyte effect. Monocytes/macrophages (promonocytes in the bone marrow, circulating monocytes, tissue macrophages) play a major role in the induction and regulation of immune reactivity.

After a year of stripping back its head count and pipeline, Carisma Therapeutics is now cutting down to the bone and laying ...

Pulmonary sarcoidosis is a lung disease characterized by granulomas—tiny clumps of immune cells that form in response to inflammation ...

D. Boral Capital lowered the firm’s price target on Carisma Therapeutics (CARM) to $1 from $12 and keeps a Buy rating on the shares after the ...

During a live event, Catherine J. Lee, MD, MS, discussed the mechanism of action of approved therapies for chronic ...

PHILADELPHIA, PA — Carisma Therapeutics Inc. (Nasdaq: CARM) has announced a revised operating plan as it evaluates a range of ...

Mechanisms that mediate interactions between microglia, endothelial cells, and macrophages and how these contribute to changes in behavior are discussed. • Sensitization of microglia and ...

Tumor-associated macrophages (TAMs) are essential components of the immune cell stroma of hepatocellular carcinoma. TAMs originate from monocytic myeloid-derived suppressor cells, peripheral blood ...

CD47-amyloid-β-CD74 signaling is a key driver of adaptive immunosuppression in sepsis, suppressing B cells and impairing ...

perhaps by accelerating lipid accumulation or macrophage chemotaxis. Proliferation is probably an early event, followed by a chronic process that provides an essential fibrous cap that prevents ...