One emerging approach involves targeting liver sinusoidal endothelial cell (LSEC) glycolysis, which has been linked to inflammation and fibrosis. Quercetin, a naturally occurring flavonoid found ...

LSECs are lining the liver sinusoids, a position that puts them in direct contact with antigens in the blood. This location, combined with their extraordinary clearance and tolerogenic function ...

Hepatic stellate cells are located along the specialized blood capillaries of the liver, known as sinusoids. They are known to drive liver fibrosis, but their actual physiological functions and ...

Researchers provide a conceptual overview of liver vasomics, including the classification of vascular phenotypes in the liver.   Chronic liver diseases are closely linked to complex hemodynamic ...

The adjacent liver cells were enlarged, with a clear cytoplasm containing vacuoles and coarse fragments of bile pigment, and in some of the cells fat droplets were observed. The sinusoids in the ...

The earliest changes in stellate cells are likely to result from paracrine stimulation by all neighboring cell types, including sinusoidal ... abundant cell type in liver, are a potent source ...

Haemolytic disease of the fetus and newborn (HDFN) occurs when there is transplacental passage of maternal immunoglobulin G ...

Publication supports Topas’ approach to generating immune tolerance through in vivo autoimmune disease model data in type 1 diabetes and multiple sclerosis Topas’ platform leverages the capability of ...