A study in Nature Genetics uses organotypic gut models to reveal genome-wide genetic determinants of Shigella colonization, spotlighting type III secretion system effectors as crucial for early ...

Neurons talk to one another using electricity. If you could hear these impulses, they might sound like constant, rapid-fire ...

The mechanism that lung epithelial cells regulate immune responses during chronic injury still remains unclear. Here, we combined single-cell RNA sequencing with spatial transcriptomics to track ...

Euclid, Box 8124, St. Louis, MO 63110, USA; [email protected] Objective The technology for the growth of human intestinal epithelial cells is rapidly progressing. An exciting possibility is that ...

This technique requires less donor tissue than previously used for conventional autografting and does not need a specialist laboratory for cell expansion. Although long-term results are awaited, this ...

Although the corneoscleral limbus is acknowledged as the site of corneal epithelial stem cells no anatomical niche for such cells has yet been described. The authors undertook to re-evaluate the ...

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Methods: In this study, we integrated scRNA-seq data with bulk RNA-seq profiles from esophageal cancer tissues to construct a comprehensive cellular atlas, focusing on the transcriptional ...