Juvenile dermatomyositis (JDM) is a rare autoimmune condition with insufficient biomarkers and treatments, in part, due to incomplete knowledge of the cell types mediating disease. We investigated ...

Objectives Myositis is a heterogeneous family of diseases including dermatomyositis (DM), immune-mediated necrotising myopathy (IMNM), antisynthetase syndrome (AS) and inclusion body myositis (IBM).

He was admitted to the acute care floor and diagnosed with juvenile dermatomyositis and found to be positive for anti-Mi-2 alpha, anti-Mi-2 beta, and anti-MDA-5 antibodies. He gradually improved with ...

WEDNESDAY, Feb. 26, 2025 (HealthDay News) -- Dermatomyositis (DM) and clinically amyopathic DM (CADM) are often misdiagnosed, according to a research letter published online Feb. 26 in JAMA ...

ABSTRACT: Introduction: This abstract reports a case of calcinosis cutis, a rare complication of acne vulgaris, in a 30-year-old woman. Acne vulgaris is a common skin disease characterized by various ...

Gottron papules are red or violet bumps that form on the outside joints of the hand. They are caused by a rare inflammatory muscle disease called dermatomyositis. In addition to classic skin changes, ...

Diagnostic objectives include: Identify the muscle and cutaneous signs and symptoms of Dermatomyositis (DM) Exclude other causes of muscle weakness (e.g., inherited, infectious or endocrine ...

Since patients with refractory Dermatomyositis (DM) may not respond to existing treatment options, there remains an unmet medical need for more therapeutic alternatives. There are now several drug ...

Study Rundown: Dermatomyositis is an autoimmune condition driven by type I interferon dysregulation. Current treatments fail to provide effective symptom control, highlighting the need for targeted ...

Interstitial pneumonia is the most common and serious secondary lesion of dermatomyositis. In some cases, patients may develop severe acute pneumonia that can quickly progress to respiratory failure, ...