BACKGROUND: Viral cardiac infection represents a significant clinical challenge encompassing several etiological agents, disease stages, complex presentation, and a resulting lack of mechanistic ...

Originally published10 Apr 2007https://doi.org/10.1161/CIRCULATIONAHA.105.592345Circulation. 2007;115:1933–1947 It has variably been estimated that between 800 000 ...

From Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (F.L.N.); Epidemiological Cardiology Research Center, Department of Epidemiology, and ...

Background—Sudden cardiac death in children is a rare but devastating event. Experts have debated the merits of community-based screening programs using an ECG and targeting 2 potential high-risk gro ...

Background— This study assessed functional performance, calf muscle characteristics, peripheral nerve function, and quality of life in asymptomatic persons with peripheral arterial disease (PAD). Met ...

From the VA Medical Center, Minneapolis, MN. So now, with national screening programs gearing up around the world, we learn from these new studies that the target condition may be in steep decline.

Background—Premature atrial contractions (PACs) are independent predictors of atrial fibrillation, stroke, and death. However, little is known about PAC frequency in the general population and its as ...

Abstract—Unstable angina is a critical phase of coronary heart disease with widely variable symptoms and prognosis. A decade ago, a classification of unstable angina based on clinical symptoms was in ...

Heart failure is one of the main causes of mortality in the developed world. It has various underlying causes such as cardiomyopathy, coronary artery disease, hypertension, and diabetes, which lead to ...

Background—Patients with mechanical heart valves require life-long anticoagulation. We report here the first large and comparative series of consecutive patients anticoagulated with low molecular wei ...

A comprehensive literature search was conducted from September 14, 2022, to November 22, 2022, encompassing studies, reviews, and other evidence on human subjects that were published in English from ...

Background—Prior studies have demonstrated low use of implantable cardioverter defibrillators (ICDs) as primary prevention, particularly among women and blacks. The degree to which the overall use of ...