A network meta-analysis combines the evidence from existing randomised trials about the comparative efficacy of multiple treatments. It allows direct and indirect evidence about each comparison to be ...

Correspondence to Professor Morten Lindbaek, Department of General Practice, Antibiotic Centre for Primary Care, Oslo, 0317, Norway; morten.lindbak{at}medisin.uio.no If you wish to reuse any or all of ...

Correspondence to Dr Igho J Onakpoya, Nuffield Department of Primary Care Health Sciences, University of Oxford, Centre for Evidence-Based Medicine, Oxford OX2 6GG, UK; igho.onakpoya{at}phc.ox.ac.uk ...

Correspondence to Cole Wayant, Oklahoma State University Center for Health Sciences, Tulsa, OK 74107, USA; cole.wayant{at}okstate.edu Recent proposals to change the p value threshold from 0.05 to ...

Correspondence to: Professor Murray Skeaff, Department of Human Nutrition, University of Otago, P.O. Box 56, Dunedin 9054, New Zealand; murray.skeaff{at}otago.ac.nz If you wish to reuse any or all of ...

Do you catch up on valuable rest time once a week at your local journal club? Or doze while somebody presents an article that has been allocated to them, without reference to “question,” “search ...

Objectives Failure to recognise and respond to patient deterioration in an appropriate and timely manner has been highlighted as a global patient safety concern. Early Warning Scores (EWSs) using ...

Objectives The EBM+ programme seeks to ensure that existing evidence of mechanisms is systematically evaluated when assessing the effectiveness of an intervention or the effects of an exposure. Basing ...

Background low back pain (LBP) is often over-diagnosed and over-treated, leading to unnecessary healthcare costs and patient harm. Major international clinical guidelines recognize that most people ...