San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

Judges declare the 2020 conviction of the former NFL Defensive Player of the Year is ‘legally invalid’ after finding his race ...

The San Francisco 49ers have suspended linebacker De’Vondre Campbell for three games – the rest of the regular season – after ...

The 49ers just lost 29-17 to the Miami Dolphins. Here are the 49ers' grades for this performance. QUARTERBACK: C Brock Purdy ...

MIAMI -- This is the live blog for the San Francisco 49ers' Week 16 road game against the Miami Dolphins. This will be ...

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

Tua Tagovailoa threw for 215 yards and a touchdown, Jason Sanders nailed five field goals, and the Miami Dolphins kept their ...

San Francisco 49ers at Miami Dolphins Preview: The 6-8 San Francisco 49ers travel to Miami to take on the 6-8 Dolphins. After ...

Winters (chest) was a full participant in Thursday's practice. Winters picked up a chest issue in Sunday's loss to Miami, but his ability to practice in full Thursday suggests that he's not ...

The 49ers have made a couple of roster moves, while also shutting down a defensive player for the season’s final two games. San Francisco announced left tackle Trent Williams has been placed on ...