Oncogene permanent activation in a single targeted cell of zebrafish together with a reprogramming factor transient activation is sufficient to induce the malignant transformation of the cell and ...

Specifically, we used a transgenic mouse line (Rlbp1-CreERt2 x LSL-TdTomato) that enabled us to restrict Cre recombination only in MG in a tamoxifen-dependent manner, and thereby regulate the ...

As a vertebrate, the zebrafish possesses many genes that perform the same or similar functions in mammals and therefore also in humans. Approximately 70 percent of zebrafish genes are also present in ...

Zebrafish have an impressive capacity to regenerate neurons ... As about 5–10% of the PCs are able to escape Tamoxifen-mediated apoptotic ablation, it could still be possible that this small fraction ...

The emergence of various liver disease models and availability of transgenic tools to visualize and manipulate macrophages have made the teleost zebrafish (Danio rerio) an attractive new vertebrate ...