A precision medicine workflow integrating proteomics and personalized xenograft models was developed and applied to an ...

Metastatic Dissemination claim ... This observation starkly contrasts with previous literature where oncogenic KRAS expression in zebrafish led to significant hyper-proliferation and abnormal growth, ...

Here, using an optogenetic approach we permanently turn on an oncogene (KRASG12V) in a single cell of a zebrafish brain that, only in synergy with the transient co-activation of a reprogramming factor ...

Early treatments may keep the bone from breaking. Metastatic cancer weakens bones. That makes it easier for them to break when you fall or get hurt. It’s also possible for weak bones to break ...

Cancer metastasis, the spread of cancer to organs, is a major cause of cancer-related deaths. Once cancer spreads to multiple organs, conventional treatments like surgery, radiation, and ...

Metastatic breast cancer (MBC) or stage IV breast cancer is when cancer spreads beyond the breast and regional lymph nodes to distant sites like bones, liver, lungs or brain. Breast cancer cells ...

Journal of Nuclear Medicine March 2025, jnumed.124.269299; DOI: https://doi.org/10.2967/jnumed.124.269299 ...

Metastatic melanoma is the most aggressive form of skin cancer. In an effort to achieve targeted therapy for metastatic melanoma, researchers recently developed a new radioactive drug that emits ...

The study, published in EMBO Molecular Medicine, shows that a process called chaperone-mediated autophagy (CMA) may function as a natural defense mechanism against metastases. Cancer remains one ...

Metastatic prostate cancer is cancer that began in the prostate but has spread to other parts of the body. There's no cure, but there are a number of effective treatments you can discuss with a ...