Abstract: Microinjection of zebrafish larvae is one of the most common procedures in biomedical experiments. Majority of microinjection work of zebrafish larvae in the laboratory is operated manually.

We integrate several apical end points, i.e., embryonic development, survival ... exposure impacted critical molecular processes involved in the metabolism of zebrafish males, which in turn affected ...

The heart is a never-stopping engine that relies on a formidable pool of mitochondria to generate energy and propel pumping. Because dying cardiomyocytes cannot be replaced, this high metabolic rate ...

Abstract: Objective: Zebrafish larva heart microinjection is a widely used technique in cardiac disease study. Compared with intensively researched rotation control of spherical or nearly spherical ...

Development, Aging and Regeneration Program, Center for Genetic Disorders and Aging Research, Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, United States Department of Biochemistry, ...

This important study applies an innovative multi-model strategy to implicate the ribosomal protein (RP) encoding genes as candidates causing Hypoplastic Left Heart Syndrome ... effect during ...

Zebrafish, due to their genetic similarity ... The findings call for strengthened urban runoff control and the development of advanced water treatment systems to curb aquatic exposure.

The mesodermal tissues that give rise to the heart first become evident when the embryo is undergoing the process known as gastrulation. In the human, this occurs during the third week of development, ...

Edited by Eric N. Olson, University of Texas Southwestern Medical Center, Dallas, TX, and approved January 13, 2017 (received for review March 29, 2016) ...

recent studies in zebrafish and mice have elegantly shown that cardiac injury reanimates the epicardium and its derivatives to modulate tissue repair. 6 This review will summarize the dynamic roles of ...

In a publication in Nature Climate Change, researchers have looked at zebrafish that they had specially bred over seven generations to tolerate higher maximum water temperatures. "In the research ...