"When you are dealing with an organism like the young larval zebrafish, which is still in development and might ... we hadn't ...

The millimeters-long, translucent zebrafish may not get depressed ... picture of how antidepressants work in the brain, potentially leading to the development of safer and more effective drugs ...

The preclinical evaluation of drug-induced cardiotoxicity is an important stage in the drug development process; however, ...

“In this system where we record from the whole brain, we might start to understand what those rules are.” While it’s not yet clear whether insights gleaned from studies on fish will translate to other ...

A new fully automated in vivo screening system (AISS) has been developed to transform drug evaluation by enabling rapid, precise, and non-invasive multi-organ imaging in zebrafish. Integrating cutting ...

Michael Barresi’s research interests are focused on how glial cells help wire the nervous system in the embryonic zebrafish brain. His lab discovered that ... Evolution and Development 8 (1): 101–10.

In vertebrate retinas, specialized photoreceptors responsible for color vision (cone cells) arrange themselves in patterns ...

During the first 72 hours in particular, extracellular vesicles—nanoparticles enclosed in cell membranes—play a significant role in the embryonic development of zebrafish. This is the result ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

The development steps that take one month for a human embryo are gone through by a zebrafish embryo in one day – an enormous time saving for scientists. The splendid colour of the adult fish starts to ...

Zebrafish are unassuming and undemanding. Almost every child knows that – at least any child that has kept fish in an aquarium. Since the beginning of the 20th century, these fish have been one of the ...