Wallerian degeneration (WD) following cerebral infarction is detectable on T2-weighted images in advanced stages. Early WD can be identified within 14 days using diffusion-weighted imaging (DWI).

Wallerian degeneration occurs distal to the injury site. Because the connective tissues are intact, typically recovery is complete. Similar injury Results from compression by tumors or masses.

J Neuroinflammation. 2018 Jun 26;15 (1):192. doi: 10.1186/s12974-018-1222-5. Lindborg JA, Mack M, Zigmond RE. (2017) Neutrophils are critical for myelin removal in peripheral nerve injury model of ...

Wallerian degeneration (WD) after ischaemic stroke is a well known phenomenon following a stereotypical time course. Whereas conventional magnetic resonance imaging fails to detect signal intensity ...

Wallerian degeneration is a simple and well-established system to investigate how damaged axons execute their destruction (Waller, 1850). Upon axonal injury (axotomy), the axon separated from the soma ...

The US Food and Drug Administration (FDA) has granted orphan drug designation (ODD) to Neuraptive Therapeutics’ NTX-001, a treatment kit containing fusogen, for peripheral nerve injury repair. The ...

Wallerian degeneration is executed by an NMN-SARM1-dependent late Ca (2+) influx but only modestly influenced by mitochondria. Cell Rep. 13, 2539–2552. doi: 10.1016/j.celrep.2015.11.032 ...

During early Wallerian degeneration, axons degenerate and Schwann cells adopt a specific response to injury: the repair program (Gerdts et al., 2016). Specifically, denervated Schwann cells lose their ...

The findings were published in an article, “ Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration,” in the journal Science Advances. Nerve ...