Both the Senju, Uzumaki and Uchiha clans share Hagoromo Otsutsuki as their ancestor. Hagoromo had two sons, Indra and Asura.

Together with the Rinnegan and Sharingan ... Although Naruto is part of the Uzumaki Clan, he is very related to the Senju Clan as they share descendants and the two clans are close allies ...