The phrenic nerve controls the diaphragm, the dome-shaped muscle that is primarily responsible for breathing. Contraction of the diaphragm expands the lungs and draws air into them.

The phrenic nerve can become damaged during surgeries to the neck, chest or heart, epidural injections, injuries from a car accident or fall, or chiropractic manipulations to the neck.

"Because hiccups are caused by the irritation of the phrenic nerve, which is part of the central nervous system, longer ...

Trial results showed consistent improvement in sleep disordered breathing, arousals, sleep architecture, and daytime sleepiness through 5 years. MINNETONKA, Minnesota, Oct. 21, 2020 /PRNewswire ...

Researchers examined patients with central sleep apnea after 5 years of treatment with transvenous phrenic nerve stimulation therapy. This article is part of MPR’s coverage of the CHEST Virtual ...

Long-Term Follow-Up after Phrenic Nerve Reconstruction for Diaphragmatic Paralysis: A Review of 180 Patients. Journal of Reconstructive Microsurgery, 2016; DOI: 10.1055/s-0036-1588018; ...

Evidence-based recommendations on phrenic nerve pacing for congenital central hypoventilation syndrome. This involves direct stimulation of the phrenic nerve, to produce the inhalation phrase of ...

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In 1937, Dr Huang stimulated the phrenic nerve of the rabbit with electricity to induce respiration. Later Sarnoff conducted the same experiment on a cat, a rabbit, a dog and a monkey. In 1949, Dr ...

The acquisition of neuronal identity through distinct transcriptional programs is critical for establishing synaptic specificity during development. Despite evidence that transcriptional programs ...