The phrenic nerve controls the diaphragm, the dome-shaped muscle that is primarily responsible for breathing. Contraction of the diaphragm expands the lungs and draws air into them.

The phrenic nerve can become damaged during surgeries to the neck, chest or heart, epidural injections, injuries from a car accident or fall, or chiropractic manipulations to the neck.

The acquisition of neuronal identity through distinct transcriptional programs is critical for establishing synaptic specificity during development. Despite evidence that transcriptional programs ...

In 1937, Dr Huang stimulated the phrenic nerve of the rabbit with electricity to induce respiration. Later Sarnoff conducted the same experiment on a cat, a rabbit, a dog and a monkey. In 1949, Dr ...

Researchers followed 180 people treated with phrenic nerve reconstruction for chronic paralysis of the diaphragm for a median of 2.7 years, assessing their physical function and reported outcomes.

Researchers examined patients with central sleep apnea after 5 years of treatment with transvenous phrenic nerve stimulation therapy. This article is part of MPR’s coverage of the CHEST Virtual ...

Phrenic nerve stimulation with the remedē System (Respicardia Inc) led to significant reductions in central apnea index (CAI), hypoxia, arousals, improved sleep quality, and overall quality of ...

Evidence-based recommendations on phrenic nerve pacing for congenital central hypoventilation syndrome. This involves direct stimulation of the phrenic nerve, to produce the inhalation phrase of ...

Long-Term Follow-Up after Phrenic Nerve Reconstruction for Diaphragmatic Paralysis: A Review of 180 Patients. Journal of Reconstructive Microsurgery, 2016; DOI: 10.1055/s-0036-1588018; ...