A dual-target CAR T cell therapy approach shows promise for slowing tumor growth in a notoriously aggressive and fast-growing brain cancer. Tumors became smaller after the experimental CAR T cell ...

Background: In human medicine, nucleated red blood cells (NRBCs) in the peripheral blood have been associated with a poor prognosis and increased mortality in critically ill patients. In critically ...

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We thank Bruce Vallance for their gift of Il18 −/− mice. NJW was supported by both an Ontario Graduate Scholarship and Canadian Graduate Scholarship, and this project was funded by Grants from the ...

While the immunomodulatory pathways initiated in immune cells contribute to therapeutic response, their activation in cancer cells play a role in cancer progression. Also, many of the aberrantly ...

Objective Intestinal epithelial cells (IECs) at the internal/external interface orchestrate the mucosal immune response. Paneth cells secrete antimicrobial peptides and inflammatory mediators, protect ...

Stem cell therapy has shown potential to reduce liver fibrosis. This report describes the management of a dog with CH with a mesenchymal cell-based approach. A 13-year old dog was presented with ...

Abstract: Red blood cell counting is one of the most requested blood tests and can be effectively done by the dedicated equipment. In this paper, we proposed the two-stage circular Hough transform as ...

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