Detection methods include DAPI staining for SAHFs and immunofluorescence ... It can support both cell survival and aging. Activation occurs through two pathways: canonical, prompted by cytokines, ...

Abstract: This study explores the degradation behavior of cable insulation under simulated aging conditions, specifically focusing on monitoring thermal properties. The insulations, used in nuclear ...

Regular cold exposure boosts the body’s natural cell-repair system and strengthens its response ... This adaptation could offer protection against disease and aging, hinting that cold acclimation may ...

The manuscript utilizes a previously reported misfolding-prone reporter to assess its behaviour in ER in different cell line models. They make two interesting observations: (1) Upon prolonged ...

NEB (nuclear ... (C) Immunofluorescence staining of BiP and ER-FlucDM-eGFP in interphase cells. Single Z-slice images were shown. Scale bar, 10 μm. Three independent experiments. Figure S6. MG132, ...

In a paper for Nature Communications, Mark Sanborn and co-authors from the College of Medicine announced the open-source tool to find aging—or senescent—cells in organs and tissues.

Halting the relentless march of so-called 'zombie cells' that drive aging and age-related diseases could be a step closer following a University of Dundee breakthrough. Experts at the University's ...