Novartis has reported positive efficacy and safety outcomes from its Phase III clinical programme for OAV101 IT (onasemnogene ...

ALS, which is also known as Lou Gehrig's Disease, is a rare neurological disease that affects motor neurons — the nerve cells ...

Mitsubishi Tanabe Pharma America, Inc. (MTPA) today announced the presentation of eleven abstracts covering research in amyotrophic lateral sclerosis (ALS) at the 2025 Muscular Dystrophy Association ...

ATH-434-201 is a 77-patient, randomized, double-blinded, placebo-controlled effort – the “gold standard” of study designs.

The paper describes a novel approach for inferring features of synaptic networks from recordings of individual cells within the network. The paper will be a valuable contribution to those studying ...

Abstract: The brain is a computing machine that receives input signals from sensory neurons, calculates best responses to changing environments, and sends output signals to motor muscles ... By ...

SMN deficiency leads to motor neuron death, ultimately causing the muscle weakness ... FIREFISH study in SMA type 1 The open-label Phase 2/3 FIREFISH study (NCT02913482) enrolled 62 infants, ages 1 to ...

The open-label Phase 1/2 study, called EPISOD1 (NCT06100276) is intended to… People with diabetes or high cholesterol may be less likely to develop amyotrophic lateral sclerosis (ALS) or other motor ...

These developmental stages in rats and mice yield DRG neuron cultures with similar percentages of pseudo ... To minimize contamination from motor axons of the ventral root, a ventral root rhizotomy ...

Enhancing levels of "healthy fats" like omega-3s in the brain could be beneficial in motor neuron disease (MND) finds a new study in fruit flies and brain cells, led by UCL researchers. Previous ...