Furthermore, we show that cell-free NETs in vitro induce a profibrotic phenotype in hepatic stellate cells (HSCs) and proinflammatory monocytes. In vivo, neutrophil depletion using anti-Ly6G antibody ...

In eight tumors where patients failed immune checkpoint inhibitor (ICI) treatment, Plinabulin + radiation + PD-1 inhibitors demonstrated ...

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional ...

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional Chinese medicine ...

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition ...

Results: Analyses demonstrate the presence of 3 core cell populations in the untreated sample: monocytes expressing Plac8 and Ms4a4c, phagocytic macrophages expressing Mrc1 and Ccl8, and reparative ...

Objective— Dendritic cells (DC) accumulate in atherosclerotic arteries where they can modulate atherogenesis. We investigated whether plasmin might alter the function of human DC. Methods and Results— ...

Introduction Since the early reference to plasmacytoid dendritic cells (pDCs) in the paracortical area of reactive lymph nodes in 1958 by Lennert and Remmele, [1] an abundance of new information ...

Objective CD14+ monocytes, play pivotal role, in SLE pathogenesis through enhanced production of B-cell activating factor (BAFF), a major cytokine driving B-cell maturation into ...