Researchers at the University of Cologne and University Hospital Cologne have determined that the novel mRNA-based COVID-19 ...

Selectively inactivating a molecular switch that turns on the gene Nr4a1 in monocytes but not macrophages leads to the loss of patrolling monocytes, which play an important role in suppressing ...

The monocyte effect. Monocytes/macrophages (promonocytes in the bone marrow, circulating monocytes, tissue macrophages) play a major role in the induction and regulation of immune reactivity.

Several reports have revealed definitive in vivo evidence of the activity of MIF in a model of SLE, demonstrated a novel role for MIF in monocyte/macrophage recruitment, and showed that MIF ...

(A) Volcano plot of DEGs in monocytes/macrophages between NC and CRC samples in the GSE164552 dataset. (B) Venn diagrams of common DEGs up- or down-regulated across the six scRNA-seq datasets (NC vs.

Johnson & Johnson announced that the FDA has approved TREMFYA, or guselkumab, the first and only IL-23 inhibitor ...

Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...