Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls ...

BACKGROUND: Despite the high morbidity and mortality of heart failure with preserved ejection fraction (HFpEF), treatment ...

Johnson & Johnson announced that the FDA has approved TREMFYA, or guselkumab, the first and only IL-23 inhibitor ...

Horsham: Johnson & Johnson has announced that the Company ahs received approval from the U.S. Food and Drug Administration ...

When they administered the modified macrophages into the lungs of mice via the trachea, they saw reduced inflammation caused by hypoxia, and monocyte recruitment was halted. Four weeks after ...

Monocytes are crucial immune cells that circulate in our blood and – when activated – migrate into tissue and differentiate into macrophages and dendritic cells. They’re also some of the ‘first ...

The monocyte effect. Monocytes/macrophages (promonocytes in the bone marrow, circulating monocytes, tissue macrophages) play a major role in the induction and regulation of immune reactivity.

New findings on tunneling nanotube-like structures offer critical insights into heart formation, paving the way for innovative heart disease therapies.

Using single-cell transcriptomics, they tracked dynamic changes in various cell types, including monocytes, macrophages, epidermal cells, and fibroblasts. The analysis revealed pronounced ...

LTZ is developing its own novel Myeloid Engager Platform to primarily enhance the phagocytic function of monocytes and macrophages of different polarization states to foster anti-tumor immunity.