Redesign of the potent painkiller's core prevents breathing suppression and reduces addiction-related behaviours in mice ...

In a new study, Nobel laureate David Baker and colleagues detail new methods for targeting undruggable "disordered" proteins.

Researchers have developed MiROM, a new infrared-based microscopy tool that detects protein misfolding in single cancer cells ...

A dual-drug hydrogel using dexamethasone and kartogenin supports cartilage repair by controlling inflammation and promoting ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

More than a year ago, computational scientists at the Department of Energy's Oak Ridge National Laboratory published a study ...

Aberrations in fibroblast growth factor receptors FGFR2/3 are major drivers of many cancers-including intrahepatic ...

A team of researchers at Oak Ridge National Laboratory has published a new study in the Royal Society of Chemistry’s ...

Researchers at EPFL and Kyoto University have created a stable hydrogen-rich liquid formed by mixing two simple chemicals.