Posttranscriptional regulation by microRNAs (miRNAs) is ubiquitously important in cell differentiation and tumorigenesis 1. Typically, the biogenesis of miRNAs involves sequential processing of the ...

Researchers reveal how cells in the peripheral nervous system (PNS) degrade myelin after nerve injury, a process that fails to occur in the central nervous system (CNS). The study appears in The ...

Researchers have found that Schwann cells, a special type of cells are capable of generating protective myelin sheath covers for the nerves at rates higher than earlier believed. Senior author Dr.

Takashi Baba, Alejandro Alvarez-Prats, Yeun Ju Kim, Daniel Abebe, Steve Wilson, Zane Aldworth, Mark A. Stopfer, John Heuser, Tamas Balla Proceedings of the National Academy of Sciences of the United ...

A research team led by neurobiologist Professor Claire Jacob has identified an important mechanism that can be used to control the restoration of myelin sheaths following traumatic injury and in ...

ORLANDO, Fla.--(BUSINESS WIRE)--Hesperos, a leader in recreating human biology with its’ Human-on-a-Chip ® platform, has announced a breakthrough development of a human induced pluripotent stem cell ...

Osteocalcin (OCN) is a multifunctional bone-derived hormone that modulates numerous physiological activities. OCN can cross the blood brain barrier (BBB) and thus play critical roles in neuronal and ...

The laminin-411 protein is vital for the formation of the myelin membrane by oligodendrocytes, report researchers from Japan. Furthermore, the A4G47 peptide from the E8 region of laminin-411 was found ...

Charcot-Marie-Tooth disease type 4C (CMT4C) is an early-onset, autosomal recessive form of demyelinating neuropathy. The clinical manifestations include progressive scoliosis, delayed age of walking, ...

Injured axons instruct Schwann cells to build specialized actin spheres to break down and remove axon fragments, thereby starting the regeneration process. Damaged peripheral nerves can regenerate ...