Over the past decade, an increasing number of observational studies have examined the effectiveness or safety of treatments for rheumatoid arthritis. Unlike randomized controlled trials (RCTs), ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window In this video, ...

In their recent article in Journal of Clinical Oncology, Soni et al 1 compared findings from randomized controlled trials (RCTs) in oncology with analogous observational comparative effectiveness ...

Comparative effectiveness research increasingly is being recognized as a priority area in cancer research. Although researchers have been conducting comparative effectiveness research for decades, ...

Not only is this environment one in which much of evidence-based practice is derived from studies considered "less than gold," but we find ourselves dissatisfied with having to rely on less than ideal ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. A test-negative observational study design may be best ...

Relying on one type of study often doesn’t paint the full picture of drug safety, efficacy, and economic and therapeutic benefits across the short and long term, the authors of the study wrote.

In our time at Takeda Oncology, we’ve had the opportunity to observe how real-world evidence (RWE) obtained outside of randomized controlled trials (RCTs) has been playing an increasingly important ...

The vitamin D story exudes teaching points: it offers a master class in critical appraisal, connecting the concepts of biologic plausibility, flawed surrogate markers, confounded observational studies ...