The children received ascending doses of the gene therapy and were monitored ... OAV-101 is a version of Zolgensma that is administered intrathecally, or via injection into the spinal canal, rather ...

Ajai Chari, MD, University of California San Francisco, explores the challenges that accompany integrating chimeric antigen receptor (CAR) T-cell therapies into multiple myeloma treatment.

Sex differences in the risk factors, diagnosis, treatment, and outcomes of patients with cardiovascular disease have been well described; however, the bulk of the literature has focused on heart ...

As the name suggests, their slim design is optimal for supporting your lower lumbar region, but we also think they have enough visual appeal to take your pillow arrangement to the next level.

What Are the Treatments for Spinal Stenosis? Spinal stenosis is a narrowing of the canal in your spinal column that affects mostly people age 50 and older. Nothing can cure it, but there are ...

Multiple sclerosis (MS) causes a specific type of damage, called demyelination, to the central nervous system, including the spinal cord. MS is a neurological disease. It causes the immune system ...

Mice were injected with 10 µl of 0.1% Alexa Fluor 647 conjugated cholera toxin subunit B into one hindpaw so that the most highly-innervated spinal cord sections could ... was injected into the ...

The word "myelopathy" means a problem with the spinal cord, which can lead to numbness, weakness, dysautonomia (group of conditions causing problems with involuntary movements), and more. There are ...

The ascending pathway begins in peripheral nociceptors, which encode painful stimuli and synapse onto projection neurons and interneurons in the spinal cord dorsal horn (DH). Ascending pathways ...

In this manuscript, the authors report that activation of excitatory DREADDs in the mid-cervical spinal cord can increase inspiratory activity in mice and rats. This is an important first step toward ...