Aberrant DNA methylation patterns are a characteristic feature of cancer including myeloid malignancies such as acute myeloid leukemia (AML). The mechanisms behind aberrant DNA methylation have ...

The focus of the current position is acute myeloid leukemia. Goal is to discover novel molecular mechanisms that could be targeted to develop new therapeutic approaches. Regulation of cellular ...

A highly sensitive bone marrow test could double survival rates for some groups of younger adults with acute myeloid leukemia (AML) by helping doctors identify if they might relapse up to three ...

This article aims to review the current application status and research advancements of selinexor in the treatment of acute myeloid leukemia (AML). Selinexor, as the first oral selective inhibitor of ...

Recent progress in the molecular genetics of acute myeloid leukemia (AML) has shown this disease to be more heterogeneous than previously realized. Recurrent cytogenetic and mutational changes in ...

Except when given into the CSF, these drugs enter the bloodstream and reach all areas of the body, making this treatment useful for cancers such as leukemia that spread throughout the body. Phases of ...

If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. A tumor-like collection of AML cells under the skin or other parts of the body is called a myeloid ...

Leukemia has several subtypes and survival rates vary. This study finds that taurine transporter expression is essential for the growth of multiple subtypes including acute myeloid leukemia (AML ...

Leukemia has several subtypes and survival rates vary. This study finds that taurine transporter expression is essential for the growth of multiple subtypes, including acute myeloid leukemia (AML ...

How TKIs Have Changed Frontline Treatment of Ph-Positive ALL Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph-positive ALL) is the most common genetic ALL subgroup in adulthood ...

Background: Relapsed or refractory Philadelphia chromosome-positive acute lymphoblastic leukemia (R/R Ph + ALL) and chronic myeloid leukemia in the blast phase (CML-BP) are associated with poor ...