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Differences in bone density and FRAX fracture risk scores among Black and Asian women yield greater discordance in fracture risk estimation compared with White women.
Cortical, trabecular bone measures at the distal radius and tibia, as measured by high-resolution peripheral quantitative CT, can help predict fracture risk when BMD alone shows no osteoporosis.
Study finds premenopausal bone mineral density (BMD), postmenopausal BMD, and rate of lumbar spine BMD decline to be risk factors for fracture.
Bone mineral density at the femoral neck and total hip is a potential surrogate for fracture risk in clinical trials of osteoporosis drugs, according to findings presented at the American Society ...
A meta-analysis of osteoporosis drugs showed that change in DXA BMD was a surrogate for fracture risk. If accepted by the FDA, it would 'really open up the field to a lot of new treatments.' ...
While absolute fracture risk was increased in older women and women with previous fractures for any T-score level, the inverse relationship between T-score and fracture risk achieved during ...
AUSTIN, Texas – One year of romosozumab (Evenity) followed by 1 year of denosumab (Prolia, Xgeva) was associated with improved bone mineral density (BMD) and lower fracture incidence compared ...
Validation of surrogate endpoints for fracture could potentially lead to shorter and less expensive clinical trials, possibly spurring innovations of new drugs and procedures which might otherwise ...
Increased genetic risk for Graves’ disease, autoimmune thyroiditis or hyperthyroidism is not associated with low bone mineral density or fracture risk, according to an analysis of UK Biobank data.
Femoral neck BMD, compared with the FRAX and Garvan models, had the best prognostic power for 5-year hip fracture risk among men and women.
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