DNA microarrays are an integral part of the process for therapeutic discovery, optimization and clinical validation. At an early stage, investigators use arrays to prioritize a few genes as ...

Bioprocess development has multiple stages, each with unique challenges. Often, the process development starts with comparison of multiple potential clones, which need to be characterized; tested ...

An Overview of Protein Microarrays Protein microarrays provide a valuable platform for both classical and functional proteome analysis and offer many advantages, the most important being HT ...

To facilitate the process of small-molecule target identification, we developed a global, microarray-based method for monitoring the growth of pools of yeast strains, each overexpressing a ...

Application of microarrays during process development helps to gain insight in biological processes involved in product formation, increasing process understanding.

In 1997, Juha Kononen, a postdoctoral fellow at the National Human Genome Research Institute, was pondering the significance of the recently developed DNA microarray. He was studying genetically ...

DNA microarrays (cDNA or oligos) have become commonplace and instrumentation is available to automate the workflow process of production, hybridization, and image analysis.

Though label-based protein microarrays have simple instrument requirements and use widely available reagents, the labelling process can alter the surface characteristics of the molecule in question.

Microarray analysis will not detect certain chromosome rearrangements, such as balanced translocations (reciprocal and Robertsonian translocations) and inversions because, although there has been ...

AliveDx, the global in-vitro diagnostics company dedicated to advancing patient care, today announced that its MosaiQ® instrument is registered with the U.S. Food and Drug Administration (FDA) as a ...