Five risk factors account for approximately 50% of the global burden of cardiovascular disease. How the presence or absence of classic risk factors affects lifetime estimates of cardiovascular ...

Transcatheter aortic-valve implantation (TAVI) is associated with procedure-related stroke. Cerebral embolic protection (CEP) devices may reduce embolization to the cerebral circulation and hence ...

In patients with active cancer and venous thromboembolism, whether extended treatment with a reduced dose of an oral anticoagulant is effective in preventing recurrent thromboembolic events and ...

Pulmonary-vein isolation is an effective treatment for paroxysmal atrial fibrillation. Pulsed field ablation (PFA) is a nonthermal ablation method with few adverse effects beyond the myocardium.

The cardiovascular safety of oral semaglutide, a glucagon-like peptide 1 receptor agonist, has been established in persons with type 2 diabetes and high cardiovascular risk. An assessment of the ...

A 59-year-old man with a history of metabolic dysfunction–associated steatotic liver disease had an enlarging liver mass. Biopsy showed hepatocellular carcinoma. Management decisions were made.

For patients with ER-positive, HER2-negative breast cancer, current therapies have several disadvantages, including limited efficacy in patients with ESR1 mutations. New research findings are ...

Tezepelumab is an epithelial cytokine blocker used to treat severe asthma; its efficacy and safety in patients with chronic rhinosinusitis with nasal polyps have been unclear. New research ...

The primary mission of medical schools is to train physicians who will provide excellent patient care. Pass/fail grading systems, in their current form, could threaten that goal.

For patients with IgG4-related disease, there are no approved therapies. New research findings on the efficacy and safety of inebilizumab ― a monoclonal antibody that targets and depletes CD19 ...

Whether intensive systolic blood-pressure control or standard control is better for cardiovascular risk reduction in patients with type 2 diabetes has been unclear. New research findings are ...

Residency applicants have long been advised to play it safe in their personal statement, but what if the best way to rise above the heap is to share a part of yourself you’ve been told to keep ...