A brain arteriovenous malformation (AVM) is an abnormal tangle of unusually formed blood vessels in the brain (Figure 1). Over time, these vessels can weaken and bleed into the brain itself. Brain ...

Depending on a range of factors including patient age, number of cavernous malformations, lesion size, location within critical or non-critical areas of the brain or spinal cord, presence of other ...

During development, cells grow, expand, and migrate to generate tissues and organs in a highly controlled manner.

CSIC researchers have discovered that disturbances to Ephrin B2 and EphB4 signaling pathways—essential for blood vessel formation in the brain—are linked to various vascular malformations.

A new study on the genetic causes of the PTEN Hamartoma Tumour Syndrome (PHTS) has found that inhibitors of the PI3ka pathway, commonly used as anticancer drugs, are also effective against this ...

That moment was the first sign of a rare condition that would cause her brain to slip out of her skull. Now 19, Emily has endured excruciating pain caused by Chiari malformation, a disorder where ...

Disruption of this interaction leads to the vascular abnormalities ... cerebral cavernous malformations (CCM) disease. This ...

Surgical management of brain ischemia and hemorrhage Vascular malformations Air/fat embolism Stroke in malignancy, immunosuppression, and as a consequence of systemic illnesses/conditions Spasticity ...