or wear-and-tear arthritis—occurs commonly in the joint at the base of the thumb, where the thumb meets the wrist. This joint, called the carpometacarpal (CMC) joint or the basilar joint ...

Rheumatoid arthritis usually causes pain in both ... De Quervain's tenosynovitis occurs from overuse of the thumb and wrist. The primary symptom is pain along the thumb side of the wrist.

Stage 4: Degeneration or weakness of the muscles at the base of the thumb ... injury to the wrist and conditions that pressure the median nerve at the wrist like rheumatoid arthritis, diabetes ...