ascopubs.org

Bayesian Sample Size Planning Tool for Phase I Dose-Finding Trials

Implementation of the Time-to-Event Continuous Reassessment Method Design in a Phase I Platform Trial Testing Novel Radiotherapy-Drug Combinations—CONCORDE BayeSize applies the concept of effect size ...
JSTOR Daily

Semiparametric Maximum Likelihood Estimation Exploiting Gene-Environment Independence in Case-Control Studies

This is a preview. Log in through your library . Abstract We consider the problem of maximum-likelihood estimation in case-control studies of gene-environment associations with disease when genetic ...
Nasdaq

Trevi Therapeutics Announces Positive Outcome of the Sample Size Re-Estimation Analysis in PRISM Trial for Severe Pruritus in Patients With Prurigo Nodularis

NEW HAVEN, Conn., July 13, 2020 (GLOBE NEWSWIRE) -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company focused on the development and commercialization of Haduvio ...
JSTOR Daily

On Estimation of Time-Dependent Attributable Fraction from Population-Based Case-Control Studies

Population attributable fraction (PAF) is widely used to quantify the disease burden associated with a modifiable exposure in a population. It has been extended to a time-varying measure that provides ...