V(D)J recombination is a fundamental genetic mechanism that underpins the adaptive immune response in jawed vertebrates. This process orchestrates the rearrangement of variable (V), diversity (D) and ...

In a recent study published in Nature Communications, researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications. Study: CRISPR-Cas9 ...

New findings suggest an explanation for the century-old mystery of how chromosome recombination is regulated during sexual reproduction. In most higher organisms, including humans, every cell carries ...

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during reproduction. The map marks a major step in the understanding of genetic ...

This is a preview. Log in through your library . Abstract Sweetpotato leaf curl virus (SPLCV) is a species of virus that causes substantial yield losses in sweetpotato. In this study, twenty-four ...

Distinguishing Renal Cell Carcinoma From Normal Kidney Tissue Using Mass Spectrometry Imaging Combined With Machine Learning Homologous recombination DNA repair deficiency (HRD) is a therapeutic ...