A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us.

Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

Randomised clinical trials (RCTs) remain the gold standard in evaluating therapeutic interventions, ensuring that treatment effects are not confounded by systematic errors. Central to these trials is ...

"Covariate adjustment" in the randomized trial context refers to an estimator of the average treatment effect that adjusts for chance imbalances between study arms in baseline variables (called ...

Immunocore announces randomization of first patient in the global, registrational Phase 3 clinical trial testing brenetafusp for the treatment of first-line advanced or metastatic cutaneous melanoma ...

The S2302 Pragmatica-Lung trial, led by the SWOG and run through the National Cancer Institute's National Clinical Trials Network, is a pragmatic registrational-intent study for advanced non–small ...

The aim of this research therefore was to streamline the understanding of typical causal structures in both randomized and nonrandomized clinical trials in oncology, presenting concise guidelines for ...

Elemento is the director of the Englander Institute for Precision Medicine at Weill Cornell Medicine. Sternberg is the clinical director of the Englander Institute for Precision Medicine. Khozin is ...

The SOL-R registrational trial (NCT06495918) of OTX-TKI (AXPAXLI) by Ocular Therapeutix has reached its randomization target of 555 patients.

In a 2023 position statement, the Menopause Society recommended clinical hypnosis for vasomotor symptoms, and other randomized trials have shown that therapist-delivered hypnosis can reduce the ...

HOUSTON -- A conservative dialysis strategy improved rates of kidney function compared to conventional thrice-weekly dialysis in patients with acute kidney injury (AKI) undergoing kidney replacement ...

(OXFORDSHIRE, England & CONSHOHOCKEN, Penn. & ROCKVILLE, Md., US, 18 June 2024) Immunocore Holdings plc (Nasdaq: IMCR) (“Immunocore” or the “Company”), a commercial-stage biotechnology company ...