In a prospective trial of patients with moderate to severe low back pain who were treated with the lidocaine patch, results showed improved scores on the Neuropathic Pain Scale over for the length of ...

In a paper published in the journal Neuron, researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic ...

A new study published in the journal EMBO Molecular Medicine describes the successful results of animal studies testing a novel experimental peptide designed to inhibit the receptors responsible for ...

More than 20 million people in the U.S. suffer neuropathic pain. At least 25% of those cases are classified as unexplained and considered cryptogenic sensory polyneuropathy (CSPN). There is no ...

A non-opioid designer molecule for treating chronic neuropathic pain by calming hyperactive pain-sensing neurons in the peripheral nervous system has had promising results in a preclinical study ...

Manuscript accepted for publication in Frontiers in Pharmacology, "Oral Administration of Ketamir-2, a Novel Ketamine Analog, Attenuates Neuropathic Pain in Rodent Models via Selective NMDA Antagonism ...