This document provides instructions on our online service for presubmission enquiries. Presubmission enquiries are provided purely as a service to authors (for example, to see if a manuscript is ...

Although the soma ages during life, the germ line of multicellular organisms does not. Here it is shown that Caenorhabditis elegans mutants with increased longevity turn on gene expression programs in ...

Communication between epithelial and mesenchymal cells in pancreatic cancer leads to a poor prognosis. The molecular basis for this signalling has now been revealed.

Browse the archive of articles on NatureReply to: Natively expressed AcrIII-1 does not function as an anti-CRISPR protein Januka S. Athukoralage Stephen A. McMahon Malcolm F. White ...

This guide describes how to prepare contributions for submission. We recommend you read this in full if you have not previously submitted a contribution to Nature. We also recommend that, before ...

Efforts to conserve Florida corals must now shift towards trying to develop heat-resistant strains, scientists say. Plus, what gives civet coffee its flavour and what we can learn from Brazil about ...

Neuroblastoma is a highly lethal childhood cancer that develops in the peripheral nervous system with tumour growth fuelled by the biosynthesis of polyamines. The drug difluoromethylornithine, which ...

Root-associated microbial symbionts have a strong influence over the way forest ecosystems function. The identity of the symbionts can help determine how easily trees access nutrients, sequester ...

The discovery of superconductivity in twisted bilayer graphene sparked interest in the electronic properties of similarly distorted 2D crystal lattices. The twisted structure is created by slightly ...

The extreme conditions found in the deep sea mean that this part of the planet remains largely unexplored. In this week’s issue, Tiefeng Li and his colleagues present a soft robot that can operate at ...

Pure mathematics involves the discovery of patterns between mathematical objects and using these connections to formulate conjectures. Mathematicians have deployed computers since the 1960s to help ...

Indispensable in fields such as structural biology and chemistry, X-ray free-electron lasers (FELs) generate intense, coherent beams of radiation at frequencies that are inaccessible to standard table ...