Bone-marrow-derived multipotent progenitor stromal cells — or mesenchymal stem cells (MSCs) — are the common predecessors of cells of the mesenchymal lineage, such as bone, cartilage and fat ...

Aged individuals and astronauts experience bone loss despite rigorous physical activity. Bone mechanoresponse is in-part ...

BMP9, a less-studied member of the BMP family, exhibits strong osteogenic effects on mesenchymal stem cells (MSCs ... promoted BMP9-induced ectopic bone formation in nude mice.

Mesenchymal ... formation and study the metabolic reprogramming involved. Depleting SUN1 and SUN2 proteins of the inner nuclear envelope halts adipogenic differentiation in mesenchymal stem cells ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Her study sheds new light on the potential of these cells ... formation. The paper is published in the Aesthetic Surgery ...

Mesenchymal stem cells (MSCs) are adult stem cells in several organs, including the umbilical cord, bone marrow, and adipose tissue. They have an amazing capacity to self-renew and distinguish.

We were the first lupus organization in the U.S. to support stromal cell research. In partnership with the National Institute of Allergy and Infectious Diseases, we committed nearly $4 million over ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

A new discovery has shed new light on the crucial role of the CD47 protein in bone fracture healing. Scientists have ...