Taiwanese researchers have elucidated the signaling mechanism downstream of IL-17 receptor B (IL-17RB) and shown that its blockade using a neutralizing antibody reduced pancreatic cancer tumorigenesis ...

Increasing evidence suggests that IL-17A and Th17 cells play a major role in autoimmune inflammation, but there are gaps in our understanding of IL-17RA signaling mechanisms. IL-17RA is expressed in ...

The family of interleukin-17 (IL-17) includes six molecules that respond to infection, in addition to participating in various physiological and pathological processes. A new paper in Signal ...

Immune molecules called cytokines play important roles in the body's defense against infection, helping to control inflammation and coordinating the responses of other immune cells. A growing body of ...

A case-time-control study found no association between the initiation of interleukin 17 (IL-17) receptor A inhibitors and major adverse cardiovascular events (MACEs). Researchers conducted a case-time ...

Beigene Ltd. has identified IL-17A/IL-17 receptor A (IL-17RA) interaction inhibitors reported to be useful for the treatment of cancer, psoriasis, rheumatoid arthritis, spondyloarthritis and multiple ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Inhibition of ...

This is part of a series of stories on inflammation triggered by SARS-CoV-2 infection. Other articles in the series include lectins, Covid-19 and brain injury, Covid-19 infection of monocytes, and ...

Cytokines are well-known players in the immune response, helping to control inflammation and coordinate the responses of other immune cells. However, a growing body of evidence suggests that some ...