The strength of the antibody-antigen interaction is determined by two key factors: affinity and avidity. Affinity refers to the strength of the binding between a single antibody binding site (paratope ...

Antibody responses by B cells become more specific over time in a process known as 'affinity maturation', but the role of antibody affinity for antigens in controlling B lymphocyte selection remains ...

"It is a very powerful tool that depends on three basic things: sensitivity, antigen-antibody affinity and specificity. This is where HIV comes in, because HIV is so pernicious that it mutates so ...

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate ... mutations that enhance their affinity for an antigen. As a consequence, high-affinity B cell ...

Researchers have developed new technology that could lead to the creation of a rapid point-of-care test for HIV infection ...

Antibody sequences Remaining antigens Top three humanized antibodies, 0.2~0.5 mg per strain (at least one humanized ab has an equivalent affinity with parental ab) CoA H and L chains in separate ...

“It is a very powerful tool that depends on three basic things: sensitivity, antigen-antibody affinity and specificity. This is where HIV comes in, because HIV is so pernicious that it mutates so ...

The technology described uses a nanomechanical platform and tiny cantilevers to detect multiple HIV antigens at high sensitivity in a matter of minutes. These silicon cantilevers are cheap and easy to ...