Recognition of specific antigen through the B-cell receptor (BCR) stimulates the activation of B cells, which ultimately results in the production of high-affinity antibodies and the provision of ...

and permeabilization or antigen retrieval treatments may be required to make the target or epitope accessible to the antibody. However, both fixation and permeabilization can affect immune affinity ...

Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could ...

and affinity maturation in one platform, meaning that we can go from antigen to primary hit antibodies in seven days,” said Lin. “Our technology uses the power of cells to create unique gene ...

In response to pathogens, IgE antibodies bound to mast cells through high-affinity receptors undergo cross-linking upon antigen binding. This cross-linking triggers mast cell degranulation ...

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

Antibody sequences Remaining antigens Top three humanized antibodies, 0.2~0.5 mg per strain (at least one humanized ab has an equivalent affinity with parental ab) CoA H and L chains in separate ...

How well a T or B cell sees its antigen is known as its affinity. This fundamental concept of immunology is how vaccines work ...

In principle, DOTA-PRIT consists of three sequential administrations of three reagents: (i) the bi-specific Ab construct IgG-scFv (bsAb), which has high specificity and affinity for both a tumor ...