In a significant step toward improving targeted cancer therapy, researchers from Japan have developed a novel nanocarrier ...

Affinity and avidity are two terms used in immunology and microbiology to describe binding strength between an antibody and antigen. Because both affinity and avidity involve binding strength, the two ...

Antibody responses by B cells become more specific over time in a process known as 'affinity maturation', but the role of antibody affinity for antigens in controlling B lymphocyte selection remains ...

Antigens are substances that trigger immune responses in the body. Understanding antigens is crucial for developing vaccines, monoclonal antibodies, and diagnostic assays in biotechnology.

Researchers have found that immunomodulatory antibodies with low affinity have higher anticancer activity that those with high affinity.

In addition, correlative studies could evaluate if differences in antibody-antigen affinity can mitigate T-cell exhaustion and improve tumor control. References: ...

Technology can improve on existing platforms’ sensitivity and speed by 20 times Microcantilevers coated in specific antibodies exhibited very high affinity for corresponding HIV antigens ...

This schematic outlines a four-step process to discover bispecific antibody leads in four months, rigorously qualifying candidates for affinity, cross-reactivity, developability, and yield.

“It is a very powerful tool that depends on three basic things: sensitivity, antigen-antibody affinity and specificity. This is where HIV comes in, because HIV is so pernicious that it mutates so ...