Adult T-cell leukemia–lymphoma (ATL) is a peripheral T-cell malignancy, closely associated with human T-cell lymphotropic virus type I infection. Clinically, ATL is classified into four subtypes ...

Diagnosis. HTLV-1-associated acute adult T-cell leukemia/lymphoma with bone marrow infiltration and hypercalcemia. Reaching the correct diagnosis was difficult and only possible through close ...

While most people who are infected with HTLV-1 do not exhibit any symptoms, up to 5% of infected people will develop a type of leukemia called adult T-cell leukemia/lymphoma or a chronic neurological ...

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders ...

Patients with acute myeloid leukemia who relapse after stem cell transplantation have just a small chance of survival: doctors can give them additional donor T cells to fight the cancer, but only ...

Large granular lymphocytic leukemias (LGLLs) are a heterogeneous group of rare chronic lymphoproliferative disorders characterized by the clonal ...

Ongoing research aims to address this challenge and improve CAR T therapy's effectiveness. One of the major challenges in treating B-cell acute lymphoblastic leukemia with CAR T-cell therapy is ...

Response to humanized defucosylated anti-CCR4 antibody (KW-0761) in a representative patient with acute-type adult T-cell leukemia–lymphoma. The time course of lymphocytes and adult T-cell ...